ABT-737
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-50907-5MG | 5 mg | 119,00 | Add | |
| HY-50907-1ML | 10mM/1mL | 127,00 | Add | |
| HY-50907-10MG | 10 mg | 138,00 | Add | |
| HY-50907-50MG | 50 mg | 432,00 | Add | |
| HY-50907-100MG | 100 mg | 753,00 | Add | |
| HY-50907-200MG | 200 mg | 1'239,00 | Add | |
| HY-50907-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Autophagy |
| Format | Solubility: DMSO : 50 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.96% |
| Molecular Formula | C42H45ClN6O5S2 |
| Molecular Weight | 813.43 |
| CAS-Number | 852808-04-9 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
