Almorexant (hydrochloride)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-10805A-1MG | 1 mg | 109,00 | Add | |
| HY-10805A-5MG | 5 mg | 213,00 | Add | |
| HY-10805A-1ML | 10mM/1mL | 256,00 | Add | |
| HY-10805A-10MG | 10 mg | 348,00 | Add | |
| HY-10805A-50MG | 50 mg | 1'167,00 | Add | |
| HY-10805A-100MG | 100 mg | 2'019,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Almorexant (ACT 078573) hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1][2][3][4].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Endocrinology, Neurological Disease, Apoptosis,GPCR/G Protein,Membrane Transporter/Ion Channel,Neuronal Signaling |
| Format | Solubility: DMSO : ≥ 46 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: Phase 3 |
| Purity | 99.98% |
| Molecular Formula | C29H32ClF3N2O3 |
| Molecular Weight | 549.02 |
| CAS-Number | 913358-93-7 |
| Storage Conditions | 4°C (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
