Alisertib
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-10971-5MG | 5 mg | 105,00 | Add | |
| HY-10971-1ML | 10mM/1mL | 118,00 | Add | |
| HY-10971-10MG | 10 mg | 165,00 | Add | |
| HY-10971-50MG | 50 mg | 380,00 | Add | |
| HY-10971-100MG | 100 mg | 584,00 | Add | |
| HY-10971-200MG | 200 mg | 1'090,00 | Add | |
| HY-10971-500MG | 500 mg | 1'534,00 | Add | |
| HY-10971-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity[1][2][3].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Autophagy,Cell Cycle/DNA Damage,Epigenetics |
| Format | Solubility: DMSO : 25 mg/mL (ultrasonic) |
| Grade | Clinical information: Phase 3 |
| Purity | 99.84% |
| Molecular Formula | C27H20ClFN4O4 |
| Molecular Weight | 518.92 |
| CAS-Number | 1028486-01-2 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
