Necrostatin-1


Catalog Number Pack Size List Price* Quantity
F7100-5MG 5 mg 65,00 Add
F7101-25MG 25 mg 178,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNF-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM.

Category Inhibitor
Supplier UBPBio
Regulatory Status RUO
Format Powder; no buffer
CAS-Number 4311-88-0
Storage Conditions -20°C
Tech. Data Sheet View datasheet
Link To Supplier http://www.ubpbio.com
Shipping Details Ambient temp.
Material Safety Data Sheet Download PDF