6xHis-Nedd8
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| E4100-500uG | 500 µg | 455,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
Nedd8 is an 81 amino acid Ub-like protein. It is conjugated to protein substrates in much the same way as Ub, using the E1, E2, E3 cascade. The specific E1 used is a heterodimer of APPBP1/UBA3. Two E2s have been discovered to follow called Ubc12 and Ube2F. Neddylation causes conformational change of the Cullin protein in the E3 called cullin-RING ligases (CRLs), which enhances the E3 Ub ligase activity of CRLs.
| Category | Protein |
| Supplier | UBPBio |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
| Storage Conditions | -80°C |
| Disclaimer | Shipped on dry ice - extra freight charge will occur |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.ubpbio.com |
| Shipping Details | Dry ice |
| Material Safety Data Sheet | Download PDF |
