6xHis-Sumo 2 (Q90P)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
E3250-500uG | 500 µg | 455,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like Ub, SUMO can be conjugated to its target proteins as a polymeric chain. However, SUMO 1 forms chains inefficiently as compared to SUMO 2 and SUMO 3. SUMO is conjugated to target proteins by the E1 (SAE1/SAE2), E2 (Ube2I or Ubc9), E3 (RanBP2/Nup358, amongst others). Protein sumoylation is involved in many cellular processes including gene transcription. The SUMO2(Q90P) mutant can still form polySUMO2 chains, but these chains are often resistant to desumolyation.
Category | Protein |
Supplier | UBPBio |
Regulatory Status | RUO |
Species Specificity | Hu |
Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
Storage Conditions | -80°C |
Disclaimer | Shipped on dry ice - extra freight charge will occur |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.ubpbio.com |
Shipping Details | Dry ice |
Material Safety Data Sheet | Download PDF |