6xHis-UbE2A (Rad6A)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| C1100-25uG | 25 µg | 353,00 | Add | |
| C1101-100uG | 100 µg | 610,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
Ube2A is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 95% amino acid sequence identity with Ube2B. One function of Ube2A involves the formation of Ube2A/Rad18 (an E3 enzyme) complex to monoubiquitinate proliferating cell nuclear antigen (PCNA) thus activating it to repair DNA damage. Ube2A is an X – chromosomal gene. Mutations in Ube2A have been linked to intellectual disability (ID), severely impaired speech, amongst other symptoms.
| Category | Enzyme/Substrate |
| Supplier | UBPBio |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
| Storage Conditions | -80°C |
| Disclaimer | Shipped on dry ice - extra freight charge will occur |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.ubpbio.com |
| Shipping Details | Dry ice |
| Material Safety Data Sheet | Download PDF |
