Doxorubicin hydrochloride
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-15142-50MG | 50 mg | 89,00 | Add | |
| HY-15142-1ML | 10mM/1mL | 97,00 | Add | |
| HY-15142-100MG | 100 mg | 120,00 | Add | |
| HY-15142-200MG | 200 mg | 196,00 | Add | |
| HY-15142-500MG | 500 mg | 348,00 | Add | |
| HY-15142-1G | 1 g | 613,00 | Add | |
| HY-15142-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[1][2][3].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Infection, Antibody-drug Conjugate/ADC Related,Anti-infection,Apoptosis,Autophagy,Cell Cycle/DNA Damage,Epigenetics,PI3K/Akt/mTOR |
| Format | Solubility: DMSO : 83.33 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: Launched |
| Purity | 99.6% |
| Molecular Formula | C27H30ClNO11 |
| Molecular Weight | 579.98 |
| CAS-Number | 25316-40-9 |
| Storage Conditions | 4°C (Powder, sealed storage, away from moisture and light) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
