Danoprevir


Catalog Number Pack Size List Price* Quantity
HY-10238-5MG 5 mg 229,00 Add
HY-10238-1ML 10mM/1mL 361,00 Add
HY-10238-10MG 10 mg 393,00 Add
HY-10238-50MG 50 mg 1'343,00 Add
HY-10238-100MG 100 mg 2'103,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM)[1][2]. Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM[3].

Category Antibiotics
Supplier MedChem Express
Regulatory Status RUO
Research Field Infection, Anti-infection,Metabolic Enzyme/Protease
Format Solubility: DMSO : ≥ 100 mg/mL
Grade Clinical information: Launched
Purity 99.69%
Molecular Formula C35H46FN5O9S
Molecular Weight 731.83
CAS-Number 850876-88-9
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF