Rapamycin


Catalog Number Pack Size List Price* Quantity
HY-10219-5MG 5 mg 53,00 Add
HY-10219-10MG 10 mg 77,00 Add
HY-10219-1ML 10mM/1mL 82,00 Add
HY-10219-25MG 25 mg 83,00 Add
HY-10219-50MG 50 mg 89,00 Add
HY-10219-100MG 100 mg 113,00 Add
HY-10219-200MG 200 mg 181,00 Add
HY-10219-500MG 500 mg 333,00 Add
HY-10219-1G 1 g 592,00 Add
HY-10219-2G 2 g 987,00 Add
HY-10219-5G 5 g 1'838,00 Add
HY-10219-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2].

Category Antibiotics
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Anti-infection,Apoptosis,Autophagy,Immunology/Inflammation,Metabolic Enzyme/Protease,PI3K/Akt/mTOR
Format Solubility: DMSO : 125 mg/mL (ultrasonic);Ethanol : 50 mg/mL (ultrasonic)
Grade Clinical information: Launched
Purity 99.94%
Molecular Formula C51H79NO13
Molecular Weight 914.17
CAS-Number 53123-88-9
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF