Dolutegravir
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-13238-2MG | 2 mg | 83,00 | Add | |
| HY-13238-1ML | 10mM/1mL | 116,00 | Add | |
| HY-13238-5MG | 5 mg | 126,00 | Add | |
| HY-13238-10MG | 10 mg | 209,00 | Add | |
| HY-13238-50MG | 50 mg | 501,00 | Add | |
| HY-13238-100MG | 100 mg | 780,00 | Add | |
| HY-13238-200MG | 200 mg | 1'198,00 | Add | |
| HY-13238-500MG | 500 mg | 1'546,00 | Add | |
| HY-13238-1G | 1 g | 2'034,00 | Add | |
| HY-13238-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].
| Category | Antibiotics |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Infection, Anti-infection,Metabolic Enzyme/Protease |
| Format | Solubility: DMSO : 10 mg/mL (ultrasonic;warming) |
| Grade | Clinical information: Launched |
| Purity | 99.65% |
| Molecular Formula | C20H19F2N3O5 |
| Molecular Weight | 419.38 |
| CAS-Number | 1051375-16-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
