Lenalidomide
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-A0003-100MG | 100 mg | 97,00 | Add | |
HY-A0003-1ML | 10mM/1mL | 106,00 | Add | |
HY-A0003-500MG | 500 mg | 164,00 | Add | |
HY-A0003-1G | 1 g | 265,00 | Add | |
HY-A0003-5G | 5 g | 641,00 | Add | |
HY-A0003-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Inflammation/Immunology, Apoptosis,PROTAC |
Format | Solubility: DMSO : 100 mg/mL (ultrasonic) |
Grade | Clinical information: Launched |
Purity | 99.98% |
Molecular Formula | C13H13N3O3 |
Molecular Weight | 259.26 |
CAS-Number | 191732-72-6 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |