SB-431542
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-10431-5MG | 5 mg | 91,00 | Add | |
| HY-10431-10MG | 10 mg | 135,00 | Add | |
| HY-10431-1ML | 10mM/1mL | 147,00 | Add | |
| HY-10431-50MG | 50 mg | 469,00 | Add | |
| HY-10431-100MG | 100 mg | 865,00 | Add | |
| HY-10431-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways[1][2][3].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Stem Cell/Wnt,TGF-beta/Smad |
| Format | Solubility: DMSO : ≥ 100 mg/mL;Ethanol : 11.17 mg/mL (ultrasonic;warming) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.89% |
| Molecular Formula | C22H16N4O3 |
| Molecular Weight | 384.39 |
| CAS-Number | 301836-41-9 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
