Bortezomib
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-10227-5MG | 5 mg | 89,00 | Add | |
HY-10227-1ML | 10mM/1mL | 97,00 | Add | |
HY-10227-10MG | 10 mg | 105,00 | Add | |
HY-10227-50MG | 50 mg | 150,00 | Add | |
HY-10227-100MG | 100 mg | 241,00 | Add | |
HY-10227-200MG | 200 mg | 378,00 | Add | |
HY-10227-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Apoptosis,Autophagy,Metabolic Enzyme/Protease,NF-κB |
Format | Solubility: DMSO : 50 mg/mL (ultrasonic);Ethanol : 66.67 mg/mL (ultrasonic;warming;heat to 60°C) |
Grade | Clinical information: Launched |
Purity | 99.97% |
Molecular Formula | C19H25BN4O4 |
Molecular Weight | 384.24 |
CAS-Number | 179324-69-7 |
Storage Conditions | 4°C (Powder, protect from light) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |