Bortezomib


Catalog Number Pack Size List Price* Quantity
HY-10227-5MG 5 mg 89,00 Add
HY-10227-1ML 10mM/1mL 97,00 Add
HY-10227-10MG 10 mg 105,00 Add
HY-10227-50MG 50 mg 150,00 Add
HY-10227-100MG 100 mg 241,00 Add
HY-10227-200MG 200 mg 378,00 Add
HY-10227-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,Autophagy,Metabolic Enzyme/Protease,NF-κB
Format Solubility: DMSO : 50 mg/mL (ultrasonic);Ethanol : 66.67 mg/mL (ultrasonic;warming;heat to 60°C)
Grade Clinical information: Launched
Purity 99.97%
Molecular Formula C19H25BN4O4
Molecular Weight 384.24
CAS-Number 179324-69-7
Storage Conditions 4°C (Powder, protect from light)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF