ARS-853


Catalog Number Pack Size List Price* Quantity
HY-19706-1MG 1 mg 250,00 Add
HY-19706-1ML 10mM/1mL 598,00 Add
HY-19706-5MG 5 mg 626,00 Add
HY-19706-10MG 10 mg 906,00 Add
HY-19706-25MG 25 mg 1'797,00 Add
HY-19706-50MG 50 mg 3'010,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,GPCR/G Protein,MAPK/ERK Pathway
Format Solubility: DMSO : 25 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 98.39%
Molecular Formula C22H29ClN4O3
Molecular Weight 432.94
CAS-Number 1629268-00-3
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF