6xHis-UbE2E2 (UbcH8)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| C1900-25uG | 25 µg | 353,00 | Add | |
| C1901-100uG | 100 µg | 610,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96% identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.
| Category | Enzyme/Substrate |
| Supplier | UBPBio |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
| Storage Conditions | -80°C |
| Disclaimer | Shipped on dry ice - extra freight charge will occur |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.ubpbio.com |
| Shipping Details | Dry ice |
| Material Safety Data Sheet | Download PDF |
