UBE1
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| B1100-25uG | 25 µg | 363,00 | Add | |
| B1101-100uG | 100 µg | 682,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
UBE1 is an E1 enzyme within the E1, E2, E3 cascade which conjugates Ub to protein substrates. UBE1 activates Ub by catalyzing an ATP – dependent reaction; Ub is conjugated onto the catalytic cysteine residue of UBE1 by formation of a thioester bond. The activated Ub is then passed on to a Ub-conjugating enzyme E2; Ub charged E2 binds a Ub ligase E3 that directly binds substrate proteins. Ub is transferred to the HECT domain E3s prior to being conjugated on substrate proteins. For RING domain E3s, Ub is transferred directly from an E2 to substrate proteins.
| Category | Enzyme/Substrate |
| Supplier | UBPBio |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
| Storage Conditions | -80°C |
| Disclaimer | Shipped on dry ice - extra freight charge will occur |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.ubpbio.com |
| Shipping Details | Dry ice |
| Material Safety Data Sheet | Download PDF |
