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Anti-CD8 Monoclonal Antibody (Clone:MEM-31)-PerCP Conjugated


Catalog Number Pack Size List Price* Quantity
30-2421-100 100 tests 478,00 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as alpha/beta heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as alpha/alpha homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha-beta but not alpha-alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

Category Antibody
Supplier Abeomics
Application FC, IP
Species Specificity Hu
Immunogen Crude thymus membrane fraction.
Host Ms
Clone Number [MEM-31]
Genebank 926
Isotype IgG2a
Crossreactivity Hu
Clonality Mab
Conjugation PerCP
Storage Conditions Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier https://www.abeomics.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF
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