Anti-CD19 Monoclonal Antibody (Clone:LT19)-PerCP Conjugated
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CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
|Immunogen||Daudi human Burkitt lymphoma cell line|
|Storage Conditions||Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.|
|Tech. Data Sheet||View datasheet|
|Link To Supplier||https://www.abeomics.com|
|Shipping Details||Blue Ice|
|Material Safety Data Sheet||Download PDF|