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Anti-HSP40, YDJ1 Monoclonal Antibody (Clone: 1G10.H8) - Alkaline Phosphatase

Catalog Number Pack Size List Price* Quantity
42-1334-100 100 µg 517,00 Add

* CHF, excl. 7.7% VAT and shipping costs

Product Description

Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1.

Category Antibody
Supplier Abeomics
Application WB, IP, EL
Species Specificity Yeast
Immunogen Full length protein yeast HSP40 (YDJ1)
Host Ms
Clone Number [1G10.H8]
Genebank 855661
Isotype IgG1 Kappa
Crossreactivity Yeast
Clonality Mab
Working Dilution WB (1:2000); optimal dilutions for assays should be determined by the user.
Purity Protein G Purified
Conjugation AP
Storage Conditions Store the antibody at 4°C
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier https://www.abeomics.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF
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