Anti-HSP40, YDJ1 Monoclonal Antibody (Clone: 1G10.H8) - Alkaline Phosphatase
|Catalog Number||Pack Size||List Price*||Quantity|
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Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not.Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1.
|Application||WB, IP, EL|
|Immunogen||Full length protein yeast HSP40 (YDJ1)|
|Working Dilution||WB (1:2000); optimal dilutions for assays should be determined by the user.|
|Purity||Protein G Purified|
|Storage Conditions||Store the antibody at 4°C|
|Tech. Data Sheet||View datasheet|
|Link To Supplier||https://www.abeomics.com|
|Shipping Details||Blue Ice|
|Material Safety Data Sheet||Download PDF|