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Anti-HSP40, YDJ1 Monoclonal Antibody (Clone: 2A7.H6) - ATTO 655


Catalog Number Pack Size List Price* Quantity
42-1439-100 100 µg 522,00 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. In particular, Hdj1, the first human HSP40/DnaJ protein identified, plays an important role in protein translation and folding, as well as in the regulation of HSP70 function. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1. Some studies have shown that the difference between HDJ1 and type 1 DNAJ proteins including HDJ2 and yeast YdjI is the result of the possession of a zinc finger domain by the latter, which helps in the function of protein folding.

Category Antibody
Supplier Abeomics
Application WB, IP, EL
Species Specificity Yeast
Immunogen Full length protein HSP40 (YDJ1)
Host Ms
Clone Number [2A7.H6]
Genebank 855661
Isotype IgG1 Kappa
Crossreactivity Yeast
Clonality Mab
Working Dilution WB (1:2000); optimal dilutions for assays should be determined by the user.
Purity Protein G Purified
Conjugation Atto 655
Storage Conditions Store the antibody at 4°C
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier https://www.abeomics.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF
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