(+)-Usnic acid
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-N0656A-1G | 1 g | 46,00 | Add | |
| HY-N0656A-1ML | 10mM/1mL | 50,00 | Add | |
| HY-N0656A-5G | 5 g | 77,00 | Add | |
| HY-N0656A-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium.
| Category | Biochemicals |
| Supplier | MedChem Express |
| Application | Cancer-Kinase/protease |
| Regulatory Status | RUO |
| Research Field | Cancer, PI3K/Akt/mTOR, Anti-infection |
| Format | Solubility: DMSO : 6.32 mg/mL (18.36 mM; Need ultrasonic) ; H2O : < 0.1 mg/mL (insoluble) |
| Grade | Clinical information: No Development Reported |
| Purity | 99% |
| Molecular Formula | C18H16O7 |
| Molecular Weight | 344.32 |
| CAS-Number | 7562-61-0 |
| Storage Conditions | 4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Product Line | Free sample |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Material Safety Data Sheet | Download PDF |
