(S)-LY-3381916
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-111540B-5MG | 5 mg | 204,00 | Add | |
HY-111540B-1ML | 10mM/1mL | 222,00 | Add | |
HY-111540B-10MG | 10 mg | 330,00 | Add | |
HY-111540B-25MG | 25 mg | 545,00 | Add | |
HY-111540B-50MG | 50 mg | 875,00 | Add | |
HY-111540B-100MG | 100 mg | 1'343,00 | Add | |
HY-111540B-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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(S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC50 value less than 1.5 µΜ[1]. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[2].
Category | Inhibitor |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Metabolic Enzyme/Protease |
Format | Solubility: DMSO : 300 mg/mL (ultrasonic) |
Grade | Clinical information: No Development Reported |
Purity | 99.06% |
Molecular Formula | C23H25FN2O3 |
Molecular Weight | 396.45 |
CAS-Number | 2166616-76-6 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |