Almonertinib
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-112823-5MG | 5 mg | 362,00 | Add | |
| HY-112823-1ML | 10mM/1mL | 416,00 | Add | |
| HY-112823-10MG | 10 mg | 571,00 | Add | |
| HY-112823-25MG | 25 mg | 1'059,00 | Add | |
| HY-112823-50MG | 50 mg | 1'476,00 | Add | |
| HY-112823-100MG | 100 mg | 2'034,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, JAK/STAT Signaling,Protein Tyrosine Kinase/RTK |
| Format | Solubility: DMSO : ≥ 83.33 mg/mL |
| Grade | Clinical information: Launched |
| Purity | 99.98% |
| Molecular Formula | C30H35N7O2 |
| Molecular Weight | 525.64 |
| CAS-Number | 1899921-05-1 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
