AS1269574


Catalog Number Pack Size List Price* Quantity
HY-107535-5MG 5 mg 119,00 Add
HY-107535-10MG 10 mg 195,00 Add
HY-107535-25MG 25 mg 362,00 Add
HY-107535-50MG 50 mg 571,00 Add
HY-107535-100MG 100 mg 849,00 Add
HY-107535-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions. AS1269574 has the potential for the research of type 2 diabetes[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Metabolic Disease, GPCR/G Protein,Membrane Transporter/Ion Channel,Neuronal Signaling
Format Solubility: DMSO : 250 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 98.76%
Molecular Formula C13H14BrN3O
Molecular Weight 308.17
CAS-Number 330981-72-1
Storage Conditions 4°C (Powder, protect from light)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF