IDH889
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-112289-1MG | 1 mg | 194,00 | Add | |
| HY-112289-5MG | 5 mg | 393,00 | Add | |
| HY-112289-1ML | 10mM/1mL | 432,00 | Add | |
| HY-112289-10MG | 10 mg | 647,00 | Add | |
| HY-112289-25MG | 25 mg | 1'090,00 | Add | |
| HY-112289-50MG | 50 mg | 1'534,00 | Add | |
| HY-112289-100MG | 100 mg | 2'294,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Best price guarantee – we offer you the lowest price in Switzerland. Please contact us for a quote if needed.
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Metabolic Enzyme/Protease |
| Format | Solubility: DMSO : 200 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.54% |
| Molecular Formula | C23H25FN6O2 |
| Molecular Weight | 436.48 |
| CAS-Number | 1429179-07-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
