Rineterkib


Catalog Number Pack Size List Price* Quantity
HY-114491-1MG 1 mg 164,00 Add
HY-114491-5MG 5 mg 330,00 Add
HY-114491-10MMO 10mM/1mL 416,00 Add
HY-114491-10MG 10 mg 584,00 Add
HY-114491-25MG 25 mg 1'217,00 Add
HY-114491-50MG 50 mg 2'103,00 Add
HY-114491-100MG 100 mg 3'750,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, MAPK/ERK Pathway,Stem Cell/Wnt
Format Solubility: DMSO : 200 mg/mL (ultrasonic)
Grade Clinical information: Phase 2
Purity 99.83%
Molecular Formula C26H27BrF3N5O2
Molecular Weight 578.42
CAS-Number 1715025-32-3
Storage Conditions 4°C (Powder, sealed storage, away from moisture and light)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF