Rineterkib
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-114491-1MG | 1 mg | 164,00 | Add | |
HY-114491-5MG | 5 mg | 330,00 | Add | |
HY-114491-10MMO | 10mM/1mL | 416,00 | Add | |
HY-114491-10MG | 10 mg | 584,00 | Add | |
HY-114491-25MG | 25 mg | 1'217,00 | Add | |
HY-114491-50MG | 50 mg | 2'103,00 | Add | |
HY-114491-100MG | 100 mg | 3'750,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, MAPK/ERK Pathway,Stem Cell/Wnt |
Format | Solubility: DMSO : 200 mg/mL (ultrasonic) |
Grade | Clinical information: Phase 2 |
Purity | 99.83% |
Molecular Formula | C26H27BrF3N5O2 |
Molecular Weight | 578.42 |
CAS-Number | 1715025-32-3 |
Storage Conditions | 4°C (Powder, sealed storage, away from moisture and light) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |