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VERU-111 (ABI-231) is a potent and orally active α and β tubulin inhibitor, which displays strong antiproliferative activity, with an average IC50 of 5.2 nM against panels of melanoma and prostate cancer cell lines. VERU-111 (ABI-231) suppresses tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7, and has potential for the treatment of prostate cancer.
|Application||Cancer-programmed cell death|
|Grade||Clinical information: No Development Reported|
|Storage Conditions||4°C, sealed storage, away from moisture and light; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)|
|Tech. Data Sheet||View datasheet|
|Link To Supplier||http://www.medchemexpress.com|
|Material Safety Data Sheet||Download PDF|