bpV(phen) (trihydrate)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-122818-5MG | 5 mg | 96,00 | Add | |
| HY-122818-1ML | 10mM/1mL | 104,00 | Add | |
| HY-122818-10MG | 10 mg | 146,00 | Add | |
| HY-122818-25MG | 25 mg | 261,00 | Add | |
| HY-122818-50MG | 50 mg | 406,00 | Add | |
| HY-122818-100MG | 100 mg | 621,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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bpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). bpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity[1][2][3][4][5].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Infection, Metabolic Disease, Inflammation/Immunology, Anti-infection,Apoptosis,Metabolic Enzyme/Protease,PI3K/Akt/mTOR |
| Format | Solubility: H2O : 18.18 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98% |
| Molecular Formula | C12H14KN2O8V |
| Molecular Weight | 404.29 |
| CAS-Number | 171202-16-7 |
| Storage Conditions | 4°C (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
