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MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.
|Application||Cancer-programmed cell death|
|Format||Solubility: DMSO : 120 mg/mL (172.30 mM; Need ultrasonic)|
|Grade||Clinical information: No Development Reported|
|Storage Conditions||Please store the product under the recommended conditions in the Certificate of Analysis.|
|Tech. Data Sheet||View datasheet|
|Link To Supplier||http://www.medchemexpress.com|
|Material Safety Data Sheet||Download PDF|