Bractoppin
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-126020-5MG | 5 mg | 178,00 | Add | |
| HY-126020-10MMO | 10mM/1mL | 195,00 | Add | |
| HY-126020-10MG | 10 mg | 277,00 | Add | |
| HY-126020-25MG | 25 mg | 540,00 | Add | |
| HY-126020-50MG | 50 mg | 804,00 | Add | |
| HY-126020-100MG | 100 mg | 1'199,00 | Add | |
| HY-126020-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Bractoppin is a potent and selective agent-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain (binding IC50: 74 nM). Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. Bractoppin preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Cell Cycle/DNA Damage |
| Format | Solubility: DMSO : 250 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.7% |
| Molecular Formula | C25H23FN4O |
| Molecular Weight | 414.47 |
| CAS-Number | 2290527-07-8 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
