DBPR112


Catalog Number Pack Size List Price* Quantity
HY-128778-5MG 5 mg 456,00 Add
HY-128778-10MMO 10mM/1mL 534,00 Add
HY-128778-10MG 10 mg 837,00 Add
HY-128778-25MG 25 mg 1'634,00 Add
HY-128778-50MG 50 mg 2'484,00 Add
HY-128778-100MG 100 mg 3'750,00 Add
HY-128778-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy[1].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, JAK/STAT Signaling,Protein Tyrosine Kinase/RTK
Format Solubility: DMSO : 250 mg/mL (ultrasonic)
Grade Clinical information: Phase 1
Purity 98.37%
Molecular Formula C32H31N5O3
Molecular Weight 533.62
CAS-Number 1226549-49-0
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF