DM3-SMe
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-130081-1ST | Get quote | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC50 of 0.0011 nM[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Antibody-drug Conjugate/ADC Related,Cell Cycle/DNA Damage,Cytoskeleton |
| Format | Solubility: 10 mM in DMSO |
| Grade | Clinical information: No Development Reported |
| Molecular Formula | C38H54ClN3O10S2 |
| Molecular Weight | 812.43 |
| CAS-Number | 796073-70-6 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room temperature |
| Material Safety Data Sheet | Download PDF |
