EGFR-IN-11
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-130616-5MG | 5 mg | 521,00 | Add | |
| HY-130616-10MMO | 10mM/1mL | 653,00 | Add | |
| HY-130616-10MG | 10 mg | 875,00 | Add | |
| HY-130616-25MG | 25 mg | 1'723,00 | Add | |
| HY-130616-50MG | 50 mg | 2'801,00 | Add | |
| HY-130616-100MG | 100 mg | 4'320,00 | Add | |
| HY-130616-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1[1].
| Category | Inhibitor |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,JAK/STAT Signaling,Protein Tyrosine Kinase/RTK |
| Format | Solubility: DMSO : 125 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.3% |
| Molecular Formula | C29H35N9O2S |
| Molecular Weight | 573.71 |
| CAS-Number | 2463200-44-2 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
