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Regulatory Status

Article Status


EGFR-IN-11


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-130616-5MG 5 mg 477,00 405,50 Add
HY-130616-10MMO 10 mM * 1 mL 603,00 512,60 Add
HY-130616-10MG 10 mg 810,00 688,50 Add
HY-130616-25MG 25 mg 1'485,00 1'262,30 Add
HY-130616-50MG 50 mg 2'419,00 2'056,20 Add
HY-130616-100MG 100 mg 3'737,00 3'176,50 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1.

Category Inhibitor
Supplier MedChem Express
Application Cancer-Kinase/protease
Regulatory Status RUO
Format Solubility: DMSO : 125 mg/mL (217.88 mM; Need ultrasonic)
Grade Clinical information: No Development Reported
Molecular Formula C29H35N9O2S
Molecular Weight 573.71
CAS-Number [2463200-44-2]
Storage Conditions Please store the product under the recommended conditions in the Certificate of Analysis.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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