LEO 39652
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-131707-5MG | 5 mg | 584,00 | Add | |
| HY-131707-10MMO | 10mM/1mL | 641,00 | Add | |
| HY-131707-10MG | 10 mg | 1'027,00 | Add | |
| HY-131707-25MG | 25 mg | 2'103,00 | Add | |
| HY-131707-50MG | 50 mg | 3'244,00 | Add | |
| HY-131707-100MG | 100 mg | 4'827,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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LEO 39652 is a dual-soft PDE4 inhibitor with IC50s of 1.2 nM, 1.2 nM, 3.0 nM and 3.8 nM for PDE4A, PDE4B, PDE4C and PDE4D, respectively. LEO 39652 also inhibits TNF-α with an IC50 value of 6.0 nM. LEO 39652 is used for topical research of Atopic dermatitis (AD) [1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Inflammation/Immunology, Metabolic Enzyme/Protease |
| Format | Solubility: DMSO : 25 mg/mL (ultrasonic) |
| Grade | Clinical information: Phase 1 |
| Purity | 99.51% |
| Molecular Formula | C23H23N3O5 |
| Molecular Weight | 421.45 |
| CAS-Number | 1445656-91-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
