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FNDR-20123


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-131708A-5MG 5 mg 454,00 385,90 Add
HY-131708A-10MMO 10 mM * 1 mL 499,00 424,20 Add
HY-131708A-10MG 10 mg 716,00 608,60 Add
HY-131708A-25MG 25 mg 1'266,00 1'076,10 Add
HY-131708A-50MG 50 mg 1'980,00 1'683,00 Add
HY-131708A-100MG 100 mg 3'133,00 2'663,10 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

FNDR-20123 is a safe, first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25/29/2/11/282 nM, respectively.) and inhibits Class III HDAC isoforms at nanomolar concentrations.

Category Biochemicals
Supplier MedChem Express
Application COVID-19-anti-virus
Regulatory Status RUO
Format Solubility: DMSO : 31.25 mg/mL (75.50 mM; Need ultrasonic)
Grade Clinical information: No Development Reported
Purity 98.04%
Molecular Formula C21H24ClN5O2
Molecular Weight 413.9
Storage Conditions Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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