PF-06843195
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-131972-5MG | 5 mg | 115,00 | Add | |
| HY-131972-1ML | 10mM/1mL | 126,00 | Add | |
| HY-131972-10MG | 10 mg | 204,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, PI3K/Akt/mTOR |
| Format | Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.06% |
| Molecular Formula | C20H25F3N8O4 |
| Molecular Weight | 498.46 |
| CAS-Number | 2067281-51-8 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
