nAChR agonist 1
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-133011-1MG | 1 mg | 285,00 | Add | |
| HY-133011-5MG | 5 mg | 584,00 | Add | |
| HY-133011-10MMO | 10mM/1mL | 641,00 | Add | |
| HY-133011-10MG | 10 mg | 1'027,00 | Add | |
| HY-133011-25MG | 25 mg | 2'103,00 | Add | |
| HY-133011-50MG | 50 mg | 3'244,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Neurological Disease, Membrane Transporter/Ion Channel,Neuronal Signaling |
| Format | Solubility: DMSO : 125 mg/mL (ultrasonic) |
| Grade | Clinical information: Phase 1 |
| Purity | 98.35% |
| Molecular Formula | C20H18ClNO3S2 |
| Molecular Weight | 419.94 |
| CAS-Number | 1394371-75-5 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
