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TNF-α (alpha)-IN-2


Catalog Number Pack Size List Price* Quantity
HY-134471-5MG 5 mg Inquire
HY-134471-25MG 25 mg Inquire
HY-134471-50MG 50 mg Inquire
HY-134471-100MG 100 mg Inquire
HY-134471-10MG 10 mg Inquire

* CHF, excl. 7.7% VAT and shipping costs


Product Description

TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis.

Category Inhibitor
Supplier MedChem Express
Application COVID-19-immunoregulation
Regulatory Status RUO
Grade Clinical information: No Development Reported
Molecular Formula C25H21ClF2N6O
Molecular Weight 494.92
CAS-Number [2074702-04-6]
Storage Conditions Please store the product under the recommended conditions in the Certificate of Analysis.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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