TNF-alpha-IN-2
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-134471-5MG | 5 mg | 1'001,00 | Add | |
| HY-134471-10MG | 10 mg | 1'597,00 | Add | |
| HY-134471-25MG | 25 mg | 3'053,00 | Add | |
| HY-134471-50MG | 50 mg | 4'891,00 | Add | |
| HY-134471-100MG | 100 mg | 7'867,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis[1].
| Category | Inhibitor |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Inflammation/Immunology, Apoptosis |
| Format | Solubility: DMSO : 100 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.12% |
| Molecular Formula | C25H21ClF2N6O |
| Molecular Weight | 494.92 |
| CAS-Number | 2074702-04-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
