Ingenol 3,20-dibenzoate


Catalog Number Pack Size List Price* Quantity
HY-137295-5MG 5 mg 822,00 Add
HY-137295-1ML 10mM/1mL 903,00 Add
HY-137295-10MG 10 mg 1'380,00 Add
HY-137295-25MG 25 mg 2'661,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Inflammation/Immunology, Apoptosis,Epigenetics,TGF-beta/Smad
Format Solubility: DMSO : 100 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 99.31%
Molecular Formula C34H36O7
Molecular Weight 556.65
CAS-Number 59086-90-7
Storage Conditions -20°C, 3 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF