YUM70
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-138364-1MG | 1 mg | 122,00 | Add | |
| HY-138364-5MG | 5 mg | 241,00 | Add | |
| HY-138364-1ML | 10mM/1mL | 265,00 | Add | |
| HY-138364-10MG | 10 mg | 368,00 | Add | |
| HY-138364-25MG | 25 mg | 723,00 | Add | |
| HY-138364-50MG | 50 mg | 1'153,00 | Add | |
| HY-138364-100MG | 100 mg | 1'851,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Cell Cycle/DNA Damage,Metabolic Enzyme/Protease |
| Format | Solubility: DMSO : 100 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98% |
| Molecular Formula | C21H19ClN2O4 |
| Molecular Weight | 398.84 |
| CAS-Number | 423145-35-1 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
