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YUM70


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-138364-5MG 5 mg 418,00 355,30 Add
HY-138364-10MG 10 mg 691,00 587,40 Add
HY-138364-25MG 25 mg 1'210,00 1'028,50 Add
HY-138364-50MG 50 mg 1'870,00 1'589,50 Add
HY-138364-100MG 100 mg 2'749,00 2'336,70 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model.

Category Biochemicals
Supplier MedChem Express
Application Cancer-programmed cell death
Regulatory Status RUO
Format Solubility: DMSO : 100 mg/mL (250.73 mM; Need ultrasonic)
Grade Clinical information: No Development Reported
Purity 98%
Molecular Formula C21H19ClN2O4
Molecular Weight 398.84
CAS-Number [423145-35-1]
Storage Conditions Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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