SB-612111


Catalog Number Pack Size List Price* Quantity
HY-18618-1ST Get quote   Inquire

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Product Description

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SB-612111 is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model[1].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Inflammation/Immunology, Neurological Disease, GPCR/G Protein,Neuronal Signaling
Format Solubility: 10 mM in DMSO
Grade Clinical information: No Development Reported
Molecular Formula C24H29Cl2NO
Molecular Weight 418.4
CAS-Number 371980-98-2
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room temperature
Material Safety Data Sheet Download PDF