AKT-IN-3
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-126257-5MG | 5 mg | 1'090,00 | Add | |
| HY-126257-10MG | 10 mg | 1'786,00 | Add | |
| HY-126257-25MG | 25 mg | 3'561,00 | Add | |
| HY-126257-50MG | 50 mg | 5'713,00 | Add | |
| HY-126257-100MG | 100 mg | 9'134,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells[1].
| Category | Inhibitor |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,PI3K/Akt/mTOR |
| Format | Solubility: DMSO : ≥ 100 mg/mL |
| Grade | Clinical information: No Development Reported |
| Purity | 99.29% |
| Molecular Formula | C23H23Cl2F2N5O3 |
| Molecular Weight | 526.36 |
| CAS-Number | 2374740-21-1 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
