Afatinib
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-10261-5MG | 5 mg | 61,00 | Add | |
| HY-10261-10MG | 10 mg | 89,00 | Add | |
| HY-10261-1ML | 10mM/1mL | 97,00 | Add | |
| HY-10261-50MG | 50 mg | 196,00 | Add | |
| HY-10261-100MG | 100 mg | 241,00 | Add | |
| HY-10261-200MG | 200 mg | 302,00 | Add | |
| HY-10261-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Autophagy,JAK/STAT Signaling,MAPK/ERK Pathway,PI3K/Akt/mTOR,Protein Tyrosine Kinase/RTK |
| Format | Solubility: DMSO : 100 mg/mL (ultrasonic) |
| Grade | Clinical information: Launched |
| Purity | 99.93% |
| Molecular Formula | C24H25ClFN5O3 |
| Molecular Weight | 485.94 |
| CAS-Number | 850140-72-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
