Absolute Antibody Catalog Highlights
Engineered recombinant antibodies for all
Absolute Antibody, now part of Vector Laboratories, is an ISO 9001:2015–certified manufacturer that has the vision to make recombinant antibody technology accessible to all.
Absolute Antibody offers a curated catalog of sequence-defined, animal-free recombinant antibodies, research-grade biosimilars, isotype controls and Fc-fusion proteins, engineered into formats that improve reproducibility and experimental flexibility.
Why choose recombinant antibodies from Absolute Antibody?
Key advantages at a glance
Sequence-defined & fully traceable
Each reagent is defined by its amino acid sequence, eliminating genetic drift, contamination and accidental hybridoma loss.
Batch-to-batch reproducibility
Recombinant production in serum-free mammalian systems ensures consistent performance and lot comparability.
High purity & low endotoxin
Products are manufactured under ISO 9001:2015 and tailored for demanding in vivo and diagnostic workflows.
Animal-free manufacturing
Production from synthetic genes avoids ongoing animal use and supports sustainable sourcing.
Unmatched format flexibility
The same clone can be offered in multiple species, isotypes, Fc variants, fragments and bispecific architectures.
Absolute Antibody builds its catalog by sequencing well-characterized monoclonal antibodies, expressing them recombinantly and engineering them into new, application-ready formats.
Available Antibody Formats
Full-length IgG
Including all major human and mouse IgG subclasses.
Non-IgG isotypes
IgM, IgA, IgE, IgD and IgY for specialized immunology and assay applications.
Chimeric & species-switched versions
Human, mouse, rat, rabbit, hamster and additional species on request.
Antibody fragments
scFv, Fab, Fab2, sdAb/dAb, half-antibodies and more, often with proprietary stabilizing motifs.
Fc Silent™ and Fc-engineered variants
Customized effector function, from fully silent to strongly depleting.
Bi- and Trispecific formats
Mouse bispecifics and other multispecific architectures for exploring combination targeting in vivo.
Humanization
Conversion of rodent or other non-human antibodies into human or humanized formats while preserving specificity and affinity, reducing immunogenicity and improving translational relevance.
Catalog Highlights
VivopureX™ in vivo Antibodies
Engineered mouse-anti-mouse antibodies ideal for in vivo mouse models:
- Species-matched to cut immunogenicity, Fc-engineered for depletion, agonism or blocking, and produced recombinantly for high purity, low endotoxin and maximal batch-to-batch reproducibility.
- Available in discounted bulk sizes (1–100 mg).
Immunotherapy Research Antibodies
A comprehensive panel of engineered antibodies to clinically relevant immuno-oncology targets – from PD-1, PD-L1 and CTLA-4 to emerging checkpoints like VISTA and TIGIT.
- Available as recombinant, Fc-engineered and VivopureX™ mouse-anti-mouse formats
- For powerful in vivo and in vitro cancer immunotherapy research.
Anti-Allergen Antibodies
A focused panel of antibodies to key environmental and food allergens, with many clones shown to compete with naturally occurring IgE. Available as human IgE and anti-IgE reagents, they provide standardized calibrators and positive controls for allergy diagnostics, mechanistic studies and assay development.
Infectious disease & virology antibodies
A broad collection of sequence-defined antibodies against key human and animal pathogens – including dengue, Ebola, influenza, HIV and SARS-CoV-2 – produced recombinantly for high specificity and batch-to-batch reproducibility, ideal for virology, infectious disease and vaccine development studies.
Research-grade biosimilar antibodies
Sequence-defined biosimilar antibodies matching therapeutic targets like trastuzumab, rituximab and others, produced recombinantly and free of formulation excipients – ideal as well-characterized controls for potency assays, MoA studies and preclinical biosimilar or biotherapeutic development.
Recombinant isotype & Fc controls
Panels of species- and isotype-matched recombinant isotype controls, generated using the same expression systems as VivopureX™ and catalog antibodies. Available with native or Fc Silent™ backbones, they provide robust negative controls for flow, in vivo studies and assay development.
DNA/RNA Research Antibodies
A specialized set of recombinant antibodies targeting DNA, RNA and DNA/RNA hybrids, including S9.6 and G-quadruplex binders. With high specificity and consistent performance, they support studies of RNA biogenesis, replication stress, R-loops, chromatin biology and epigenetic regulation.
Antibodies to Epitope Tags
A comprehensive collection of recombinant antibodies to common peptide tags – including classic anti-c-Myc clone 9E10, RAP and MAP tags, plus a multi-tag control protein. Offered in diverse species and formats, these reagents standardize detection, IP and purification of tagged constructs across assays and platforms.
Recombinant F4/80 Clone CI:A3-1
The classic anti-F4/80 clone CI:A3-1, a benchmark marker for murine macrophages and microglia, has been sequenced and re-expressed as recombinant and chimeric antibodies. These formats deliver high purity and batch-to-batch reproducibility for flow cytometry, imaging and functional macrophage depletion or tracking studies.
Neuroscience Research Antibodies
A growing range of recombinantly produced antibodies against neurotransmission and neurodevelopment markers, neural lineage proteins and disease targets such as amyloid beta. Offered in multiple species and engineered formats, they ensure reproducible staining, functional studies and assay development in neuroscience and neurodegeneration research.