Navinci - Taregt Specific PLA Kits
Available for PD1, EGFR, PDGFR-b, HER2, MET, VEGFR2, PD1/PD-L1, CD8/MHC-I
Naveni® PPI (Protein-Protein Interaction) Kits are target-specific in situ kits for detection of protein protein interactions in cultured cells, fresh-frozen, and FFPE samples. The primary antibody system with Navenibodies is included. No extra antibodies are needed. The assay is already optimized.
Naveni® PTM (Post Translational Modification) Kits are in situ kits for detection and quantification of post translational modifications, such as phosphorylated proteins, in cultured cells, fresh-frozen and FFPE samples. The kits contain a primary detection system with Navenibodies. No extra antibodies are needed; the assay is already optimized.
Both, the Naveni® PPI kits and the Naveni® PTM kits are based on the Naveni® Proximity Ligation Technology.
Naveni® PPI (Protein-Protein Interaction) Kits
NEW!
Naveni CD8/MHC-I Atto647N
Visualize the interaction of CD8/MHC-I in situ. The kit includes primary antibodies specific to CD8 and MHC-I, Navenibodies, and all other reagents needed to run the assay. Fluorescence readout, possible to combine with co-staining.
Naveni CD8/MHCI™ enables you to:
- Detect the specific interaction of CD8/MHCI using dual recognition
- Identify interactions of low-abundant CD8/MHCI
- Visualize CD8/MHCI in the tissue microenvironment
- Increase understanding of signaling pathwayswhere CD8/MHCI is part of
- Elucidate the potential of CD8/MHCIinteraction as a co-biomarker
Naveni® CD8/MHCI Atto647N
- Primary human anti-CD8 protein built on clone SP239 (Abcam)
- Primary human anti-MHC1 protein built on clone 5C5B7 (Protein Tech)
- The Navenibody solution has a working volume of 4000μl (sufficient for approx. 100 reactions)
Naveni PD1/PD-L1 AP
Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out.
Naveni PD1/PD-L1 Atto647N
Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Fluorescence readout, possible to combine with co-staining.
Naveni PD1/PD-L1 HRP
Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out
Naveni® PTM (Post Translational Modification) Kits
Naveni pY EGFR
The Naveni pTyr EGFR target specific assay detects phosphorylated EGFR with high specificity and sensitivity using our patented Naveni™ probe technology. The kit includes primary Navenibodies against phosphorylated EGFR and all other reagents needed to run the assay.
Naveni pY PDGFR-beta
The Naveni pTyr PDGFR-beta target specific assay detects phosphorylated PDGFRβ with high specificity and sensitivity using our patented Naveni™ probe technology. The kit includes primary Navenibodies against phosphorylated PDGFRβ and all other reagents needed to run the assay.
Naveni pY HER2
The Naveni pTyr HER2 target specific assay detects phosphorylated HER2 with high specificity and sensitivity using our patented Naveni™ probe technology. The kit includes primary Navenibodies against phosphorylated HER2 and all other reagents needed to run the assay.
Naveni pY MET
The Naveni pTyr MET target specific assay detects phosphorylated MET with high specificity and sensitivity using our patented Naveni™ probe technology. The kit includes primary Navenibodies against phosphorylated MET and all other reagents needed to run the assay.
Naveni pY VEGFR2
The Naveni pY VEFGR2 is an in situ proximity ligation assay kit for fluorescence detection of phosphorylated VEGFR2. Contrary to traditional immunofluorescence, the kit gives a high signal-to-noise ratio and is easily quantifiable.
Naveni pY PD1 AP or HRP
Visualize phosphorylated PD1 in situ. The kit includes primary Navenibodies specific to phosphorylated PD1 and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out.
