PROGEN - AAV monitoring reagents

Monitor AAV identity, yield, potency, purity and integrity

PROGEN provides an exclusive and comprehensive portfolio of reagents for AAV monitoring, including AAV antibodies, AAV titration ELISA kits, AAV standards and density gradient media.

PROGEN is DIN EN ISO13485 certified and is made up of a team of experts within AAV and the life sciences and is partnered with gene therapy experts worldwide.

AAV Antibodies

AAV Capsid Protein Antibodies

  • Analysis of denatured AAV capsid proteins
  • Detection of linear epitopes of the viral capsids VP1, VP2 and VP3 across serotypes
AAV Capsid Protein Antibody

Applications: WB, IF/ICC, affinity chromatography, Dotblot, IP

AAV Intact Particle Antibodies

  • Analysis of intact AAV particles, i.e. empty and full capsids
  • Detection of conformational epitope of the assembled capsid of certain serotypes
AAV Particle Antibody

Applications: AAV ELISAs, IF/ICC, affinity chromatography, dot blot, IP, neutralization assay

AAV Replicase Antibodies

  • Analysis of the regulatory proteins Rep78, Rep68, Rep52 and Rep40

AAV Replicase Ab

Applications: Western Blot

Human Chimeric AAV Antibodies

Testing patient sera before clinical trials ensures you know whether AAV antibodies are present in patient sera or not, resulting in a safe and efficient gene transfer. 

AAV Human Chimeric Antibodies

Applications: Dot blot, neutralization assay, serology ELISA


AAV Titration ELISAs

  • Titration of intact capsids
  • High precision and accuracy
  • Reliable serotype-specific positive controls for AAV ELISAs 

Standard ELISA: 4.5h 
Xpress ELISA: < 2h 

Simple Plex™ Assays for Viral Quantification

  • Exclusively detect intact AAV capsids in bioprocess samples 
  • Measure viral titer across a broad dynamic range
  • Quantify viral titer of AAV capsids
  • Hands free automation when using the Ella platform
AAV Simple Plex Assays

AAV Standards

AAV Empty Capsids

  • High viral particle titer
  • No additives and stabilizing proteins
  •  Serotype-specific conformational epitopes 
  • Suitable as positive control for a variety of applications

AAV VP Capsid Protein Standards

Optimize your AAV production!

  • Monitor VP1, VP2, and VP3 protein concentrations and their molar ratios
  • Optimization of yield
  • Available for AAV2, AAV5, AAV6, AAV8 and AAV9

AAV ELISA Controls

  • Can be used as positive controls with the corresponding AAV ELISAs
  • Independent controls to verify the test validity
  • They consist of fully assembled, empty AAV particles
  • Available for AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAVrh10 and AAVrh74

Dip‘n‘Check AAV

Dip'n'Check AAV Lateral Flow Tests

  • Quick and easy in-process control
  • For the semi-quantitative detection of fully
  • Uses serotype-specific antibodies
  • assembled AAV capsids
  • For crude and purified material

Details | Order

AAV Lateral Flow Test

Density Gradient Medium - OptiPrep™


OptiPrepTM is a ready-made, sterile and endotoxin-tested solution of iodixanol that works across research and clinical workflows, giving you control over your virus purification. Iodixanol can be used for full and empty capsid separation, as well as for AAV particle purification.

  • for AAV Particle Purification
  • for Full and Empty Capsid Separation

OptiPrep™ for AAV Particle Purification

Purification OptiPrep V2

OptiPrep™ for Full and Empty Capsid Separation

Separation OptiPrep V2