Bafilomycin A1
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-100558-100uG | 100 μg | 120,00 | Add | |
| HY-100558-500uG | 500 μg | 330,00 | Add | |
| HY-100558-1MG | 1 mg | 545,00 | Add | |
| HY-100558-5MG | 5 mg | 1'875,00 | Add | |
| HY-100558-10MG | 10 mg | 2'990,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis[1][2][3].
| Category | Antibiotics |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Infection, Anti-infection,Apoptosis,Autophagy,Membrane Transporter/Ion Channel |
| Format | Solubility: DMSO : 50 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.43% |
| Molecular Formula | C35H58O9 |
| Molecular Weight | 622.83 |
| CAS-Number | 88899-55-2 |
| Storage Conditions | -20°C (Powder, protect from light) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
