IWP-2
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-13912-5MG | 5 mg | 83,00 | Add | |
| HY-13912-10MG | 10 mg | 126,00 | Add | |
| HY-13912-25MG | 25 mg | 236,00 | Add | |
| HY-13912-50MG | 50 mg | 375,00 | Add | |
| HY-13912-100MG | 100 mg | 585,00 | Add | |
| HY-13912-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Cell Cycle/DNA Damage,Stem Cell/Wnt |
| Format | Solubility: DMF : 12.5 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 2 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.51% |
| Molecular Formula | C22H18N4O2S3 |
| Molecular Weight | 466.6 |
| CAS-Number | 686770-61-6 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
