ARS-853
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-19706-1MG | 1 mg | 250,00 | Add | |
HY-19706-1ML | 10mM/1mL | 598,00 | Add | |
HY-19706-5MG | 5 mg | 626,00 | Add | |
HY-19706-10MG | 10 mg | 906,00 | Add | |
HY-19706-25MG | 25 mg | 1'797,00 | Add | |
HY-19706-50MG | 50 mg | 3'010,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Apoptosis,GPCR/G Protein,MAPK/ERK Pathway |
Format | Solubility: DMSO : 25 mg/mL (ultrasonic) |
Grade | Clinical information: No Development Reported |
Purity | 98.39% |
Molecular Formula | C22H29ClN4O3 |
Molecular Weight | 432.94 |
CAS-Number | 1629268-00-3 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |